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CD154 Antibody, anti-mouse, Bi

otin, 30 µg in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-101-900
  • 2025年12月09日
  • Flow cytometry, Intracellular flow cytometry
  • hamster
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD154

    • 亚型

      hamster IgG3κ

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      MR1

    • 标记物

      Biotin

    • 适应物种

      mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      hamster

    • 应用范围

      Flow cytometry, Intracellular flow cytometry

    • 浓度

      1:10

    • 靶点

      CD154

    • 抗体英文名

      CD154 Antibody, anti-mouse

    • 抗体名

      CD154 Antibody, anti-mouse

    • 规格

      30 µg in 1 mL

    Detection of activated antigen-specific CD4+ mouse T helper cellsClone MR1 specifically recognizes the mouse CD154 antigen, a 39 kDa transmembrane glycoprotein also known as CD40L, gp39, T-BAM, TRAP, or Ly-62. CD154 is transiently up-regulated on activated CD4+ T cells and plays an important role as a costimulatory molecule in T cell/antigen-presenting cell interactions through ligation of CD40. The antibody has been shown to block the activation of antigen-presenting cells by T helper cells in vitro. Due to its transient expression within hours after activation, CD154 can be used as a marker for activated antigen-specific CD4+ T cells. Adding a CD40-blocking antibody during the stimulation of cell suspensions prevents the down-regulation of CD154. Blocking of CD40 is not required for intracellular detection of CD154 expression or if a pure population of enriched T cells is used.

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    图标文献和实验
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    • AbC Anti-Mouse Bead Kit

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    • RNA-biotin based pulldown assays for the detection of siRNA targeted genomic regions and siRNA directed histone modifications (PROT32)

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