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- 详细信息
- 技术资料
- 免疫原:
CD146
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
541-10B2
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:11
- 靶点:
CD146
- 抗体英文名:
CD146 Antibody, anti-human
- 抗体名:
CD146 Antibody, anti-human
- 规格:
30 tests in 300 µL
Detection of endothelial cells, smooth muscle cells, follicular dendritic cells, melanoma cells, and a sub-population of activated T lymphocytesClone 541-10B2 recognizes the human CD146 antigen, also known as MUC18, MCAM, Mel‑CAM, or S-endo. CD146 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily and contains five extracellular immunoglobulin (Ig)–like domains. CD146 possesses a limited tissue expression distribution, including endothelial cells, pericytes, smooth muscle cells, follicular dendritic cells, melanoma cells, and a sub-population of activated T lymphocytes. CD146 is also expressed on marrow stromal cells (MSCs). | CD146 functions as a Ca2+-independent cell adhesion molecule that is involved in heterophilic cell-cell interactions, and may be involved in the extravasion and/or homing of activated T cells. CD146 expression in melanoma is also directly associated with tumor growth and metastasis. |
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CD146 Antibody, anti-human, PE, 30 tests in 300 µL
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