- 询价
- Miltenyi Biotec
- 德国
- 130-103-665
- 2025年12月09日
- Flow cytometry
- mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
Siglec-10
- 亚型：
mouse IgG1κ
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
5G6
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
mouse
- 应用范围：
Flow cytometry
- 浓度：
1:11
- 靶点：
Siglec-10
- 抗体英文名：
Siglec-10 Antibody, anti-human
- 抗体名：
Siglec-10 Antibody, anti-human
- 规格：
100 tests in 1 mL
Identification and enumeration of siglec-10+ cells by flow cytometryClone 5G6 recognizes the sialic acid-binding Ig-like lectin 10 (Siglec-10) antigen, a member of the CD33-related group of siglecs. The cytoplasmic tail of Siglec-10 contains four tyrosines, two of which are embedded in ITIM-signaling motifs and are likely to be involved in intracellular signaling. Amongst peripheral blood leucocytes, Siglec-10 was found to be expressed on eosinophils, monocytes, and B cells. Higher levels of Siglec-10 were found on a minor subset of NK-like cells that express the CD16 low-affinity Fc receptor but lack the CD56 antigen. The molecular properties and expression pattern suggest that Siglec-10 may have evolved to function as an inhibitory receptor of the innate immune system.
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Siglec-10 Antibody, anti-human, PE, 100 tests in 1 mL
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