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- 详细信息
- 技术资料
- 免疫原:
Ly-49D
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
4E5
- 标记物:
VioBlue
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 靶点:
Ly-49D
- 抗体英文名:
Ly-49D Antibody, anti-mouse
- 抗体名:
Ly-49D Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Identification and enumeration of Ly-49D+ cells by flow cytometryClone 4E5 recognizes Ly-49D, a type II transmembrane NK-cell receptor belonging to the Ly-49 family. Members of Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. Ly-49D is a prototypic activating member of Ly-49 family and in contrast to inhibitory members, lacks a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM). A positive signal is initiated by interaction of Ly-49D with immunoreceptor tyrosine-based activating motif (ITAM) containing transmembrane adapter DAP12. Expression of Ly-49D is strain restricted and is found on subsets of NK cells in C57BL/6, C3H/He, and SJL but not in BALB/c, DBA/2, AKR, and CBA/J mice.
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Ly-49D Antibody, anti-mouse, VioBlue®, 30 µg in 1 mL
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