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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Phospho-Rb (Ser780) Rabbit mAb抗体
- 抗体英文名:
Phospho-Rb (Ser780) Rabbit mAb
- 靶点:
RB1
- 浓度:
0.3 mg/ml
- 应用范围:
IHC-P, WB
- 适应物种:
Human, Rat
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1563981
- 级别:
科研级
- 库存:
88
- 供应商:
biorbyt
- 标记物:
Unconjugated
- 克隆性:
Monoclonal
- 保存条件:
参考说明书
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
A synthetic phosphopeptide corresponding to residues surrounding Ser780 of human Rb
- 规格:
20 ul
别名:RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
免疫原:A synthetic phosphopeptide corresponding to residues surrounding Ser780 of human Rb
克隆性:R04-5B7
分子量:Calculated MW: 106 kDa; Observed MW: 110 kDa
应用稀释比例:WB: 1/500-1/1000 IHC: 1/50-1/100
防腐剂:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.
纯化:Affinity Purified
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
UniProt ID:P06400
Note:For research use only.


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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
:使用 Anti-phospho-Akt (Ser473) Rabbit mAb 对石蜡包埋的人乳腺癌组织进行免疫组织化学分析。(图 A)使用免疫组化试剂盒M&R HRP/DAB Detection IHC Kit,抗体 1:100 稀释;(图 B) 采用普通免疫组化试剂盒,抗体 1:25 稀释。 图 6 免疫组化实验检测 Erk1/2 表达 注:使用 Anti-Erk1/2 Mouse mAb与p44/42 MAPK (Erk1/2)Rabbit mAb 对正常小鼠心脏组织进行免疫
), and causes activation of KOR. Agonist-activated KOR becomes a substrate for G protein receptor kinase (GRK), which phosphorylates the Ser369 residue at the C-terminal tail of the receptor in the first step in the β-Arrestin-dependent desensitization cascade
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