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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
TLR8 Antibody抗体
- 抗体英文名:
TLR8 Antibody
- 靶点:
TLR8
- 浓度:
1 mg/mL
- 应用范围:
ELISA, ICC, IF, WB
- 适应物种:
Human, Mouse
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1238754
- 级别:
科研级
- 库存:
88
- 供应商:
biorbyt
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.The immunogen is located within amino acids 790 - 840 of TLR8.
- 规格:
0.02 mg
别名:TLR8 Antibody: CD288, Toll-like receptor 8
免疫原:TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.The 免疫原 is located within amino acids 790 - 840 of TLR8.
分子量:Predicted: 112 kDa Observed: 107 kDa
应用注释:TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
防腐剂:TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化:TLR8 Antibody is affinity chromatography purified via peptide column.
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NCBI:NP_619542
UniProt ID:Q9NR97
Note:For research use only.



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文献和实验Viral single-stranded (ss) RNA is the natural ligand for TLR7 and TLR8. Synthetic ssRNA has been shown to act as a ligand for TLR7 and TLR8. We have previously reported a novel RNA structure, referred to as stabilized immune modulatory RNA
Development of TLR7/8 Small RNA Antagonists
Toll-like receptors (TLRs) expressed by innate immune cells recognize a spectrum of microbial structures. Recent studies have provided convincing evidence that TLR7 and TLR8 play a key role in sensing viral RNAs. Under certain conditions
siRNAs is mediated by TLR7 and/or TLR8 in immune cells. Importantly, it has also been shown that the replacement of uridines with their 2ʹ-modified counterparts can prevent immune activation. Similarly, 2ʹ-modifications, particularly at the seed sequence
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