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- AntibodySystem
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- EHB86201
- 2025年12月26日
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- 保存条件：
-20℃
- 保质期：
12 months
- 英文名：
Native Human F8/Coagulation factor VIII Protein
- 供应商：
武汉益普生物科技有限公司
- 规格：
50μg/100μg/1mg
| 规格： | 50μg | 产品价格： | ￥1800.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | ￥2880.0 |
| 规格： | 1mg | 产品价格： | ￥17280.0 |
| 产品名 | Native Human F8/Coagulation factor VIII Protein |
| 货号 | EHB86201 |
| 别名 | AHF, Procoagulant component, Coagulation factor VIII, Antihemophilic factor, F8C, F8 |
| Accession号 | P00451 |
| 种属 | Homo sapiens (Human) |
| 蛋白长度 | Full-length protein (Native). |
| 预测分子量 | 267 kDa |
| 性质 | Native |
| 内毒素水平 | < 1 EU/µg as determined by LAL test. |
| 纯度 | > 90% as determined by SDS-PAGE. |
| 应用 | Bioactivity, ELISA, Immunogen, SDS-PAGE, WB |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm filtered solution in 20mM PB, 150mM NaCl, pH 7.2. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 说明 | For research use only. |
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文献和实验Nijmegen-Bethesda Assay to Measure Factor VIII Inhibitors
Hemophilia A is an inherited bleeding disorder caused by a deficiency of factor VIII coagulant activity (FVIII:C). Patients are treated with infusions of either plasma-derived or recombinant factor VIII. However, some patients develop
Identification of Mutations in the Human Factor VII Gene
It has been recognized from the early 1800s that activation of coagulation can be initiated by the exposure of subendothelial layers (tissue factor), but it was the 1940s before factor VII (FVII) was included in this event
Defects of the factor VIII gene causes (f8 ) hemophilia A, an hemorrhagic X-linked disorder. The factor VIII gene is 186 kb long with 26 exons, varying from 69 bp (exon 5) to 3106 bp (exon 14) (1 ). The factor VIII mRNA is 9028 bases
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