- ￥2160 - 19440
- AntibodySystem
- France
- AHJ28403
- 2025年12月06日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
12 months
- 英文名：
Recombinant Human CD366/HAVCR2/TIM-3 Protein, C-His (Active)
- 供应商：
武汉益普生物科技有限公司
- 规格：
50μg/100μg/1mg
| 规格： | 50μg | 产品价格： | ￥2160.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | ￥3240.0 |
| 规格： | 1mg | 产品价格： | ￥19440.0 |
| 产品名 | Recombinant Human CD366/HAVCR2/TIM-3 Protein, C-His (Active) |
| 货号 | AHJ28403 |
| 别名 | Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3, TIMD-3, T-Cell Membrane Protein 3, TIM-3, HAVCR2, TIM3, TIMD3 |
| 表达系统 | Mammalian Cells |
| Accession号 | AAL65157.1 |
| 种属 | Homo sapiens (Human) |
| 蛋白长度 | Ser22-Arg200 |
| 预测分子量 | 20.86 kDa |
| 性质 | Recombinant |
| 内毒素水平 | < 1 EU/µg as determined by LAL test. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 应用 | Bioactivity, ELISA, Immunogen, SDS-PAGE, WB |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a 0.22 μm filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 说明 | For research use only. |
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文献和实验Generation of Monoclonal Antibodies to Native Active Human Glycosyltransferases
Complex carbohydrates serve a wide range of biological functions in cells and tissues. Their biosynthesis involves more than 200 distinct glycosyltransferases in human cells, and the expression, properties, and topology of these enzymes
-bin/carddisp.pl?gene=HAVCR2&keywords=CD366 TIM3作为重要的细胞免疫负调控因子，高表达于辅助型T细胞（Thl细胞）和细胞毒性T细胞中（Tcl细胞），并产生抑制信号从而导致Thl细胞和Tcl细胞的凋亡。其配体为半乳凝素9(Gal-9)，这是一种被广泛表达的可溶性分子[7]，与TIM3分子的免疫球蛋白可变区上的寡聚糖结合，从而对Thl驱动的免疫反应产生负调控作用。当TIM3与其配体半乳凝素9(Gal-9)结合后，促进Thl细胞凋亡[8] 。也就是说
Translocation Assays of Protein Kinase C Activation
The protein kinase C (PKC) family members include at least 11 different isoforms that, based on their different requirements for activation, have been divided into three subfamilies, the Ca2+ -dependent (cPKCα, (βI , βII
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