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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
MRX-1024; D-Methionine
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
348-67-4
- 规格：
10 mM * 1 mL/1 g/5 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥330.0 |
|---|---|---|---|
| 规格： | 1 g | 产品价格： | ￥300.0 |
| 规格： | 5 g | 产品价格： | ￥500.0 |
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Methionine
CAS No. : 348-67-4
MCE 国际站：Methionine
产品活性：Methionine (MRX-1024; D-Methionine) 是一种有效的化学保护剂，它还可以通过激活 GABAA 受体来抑制神经元活性。
研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling
作用靶点：GABA Receptor
In Vitro: The incubation of human plasma with Methionine (D-methionine) and CP leads to the formation of a Pt-D-methionine complex independent of the order of addition. In plasma, an early CP hydrolysis product reacts with Methionine to form a 1:1 complex that is followed by the formation of a 2:1 compound at a later time point. The formation of these Pt-D-methionine species plays an important role in the processes by which Methionine protects mammalian organisms against CP-induced toxicities.
In Vivo: When Methionine (D-methionine) is administered along with cisplatin the cell density is 0.8±0.070 (SEM), significantly larger than in rats treated with only cisplatin (P<0.01) while not significantly different from controls or from animals treated only with D-methionine (P>0.05). When Methionine is administered alone the average cell density is 0.95±0.099 (SEM) and not significantly different from controls (P>0.05).
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