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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
BNIP3 Antibody抗体
- 抗体英文名:
BNIP3 Antibody
- 应用范围:
IHC, WB
- 宿主:
Rabbit
- 适应物种:
Human, Mouse
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb318840
- 级别:
科研级
- 库存:
88
- 供应商:
biorbyt
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 形态:
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BNIP3. The exact sequence is proprietary.
- 规格:
30 ul
别名:NIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
免疫原:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BNIP3. The exact sequence is proprietary.
应用稀释比例:WB: 1:500-1:1000
纯化:The antibody was purified by immunogen affinity chromatography.
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Entrez:664, 12176
UniProt ID:O55003, Q12983
Note:For research use only.


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文献和实验fanghuili2007 S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3.Ghavami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayko AJ, McNeill KD, Hashemi M
Bid,Bad, Bim, Bik/Nbk, Blk, Hrk, Bnip3, Nix, NOXA, PUMA and Bcl-GS). Once 'activated', these proteins are thought to facilitate, through many mechanisms, the assembly of pro-apoptotic 'multi-domain' members of the Bcl-2 family
5)、Bnip3.BimL;~[1Noxa等蛋白,它们只含有BH3结构域,具有促凋亡能力。 抑制凋亡的信号分子 如Bcl-2、Bcl-XL等大多存在于线粒体和其他细胞器 膜上,而促进细胞凋亡的Bcl-2家族蛋白分子 (如Bax、Bid等)大多存在于细胞浆中。在凋亡因子刺激下,促凋亡蛋白分子发生转录 水平增加(如p53介导的Bax、Noxa、Puma等)和翻 译后的激活和修饰。促凋亡分子的激活还包括Bax等蛋白的构象变化和多聚化、Bid等蛋 白的印割、Bad等分子的磷酸化与去磷酸化等。有意
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