- ￥630 - 3160
- DIMA BIOTECH/缔码生物
- 武汉
- PME101920
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期：
12个月
- 英文名：
Recombinant human HCRTR2 Protein with C-terminal human Fc tag
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg/50μg/100μg
| 规格： | 10μg | 产品价格： | ￥630.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥2250.0 |
| 规格： | 100μg | 产品价格： | ￥3160.0 |
| 产品类型 | ECD Proteins |
|---|---|
| 靶点 | HCRTR2 |
| Uniprot ID | O43614 |
| 别名 | OX2R, Orexin receptor 2, Hypocretin receptor 2 |
| 背景 | HCRTR2 (Orexin receptor 2 / Hypocretin receptor 2) is a G-protein coupled receptor (GPCR) expressed in the central nervous system, particularly in hypothalamic neurons. It couples to Gq and Gi/o proteins, activating PLC/Ca²⁺ signaling and modulating adenylyl cyclase and MAPK pathways. HCRTR2 regulates wakefulness, sleep-wake cycles, appetite, and energy homeostasis. Dysregulation is associated with narcolepsy, sleep disorders, and metabolic dysfunctions, making it a therapeutic target for sleep and metabolic disorders. |
| 产品英文名称 | Recombinant human HCRTR2 Protein with C-terminal human Fc tag |
| 分子结构 | HCRTR2(Met1-Lys51) hFc(Glu99-Ala330) |
| 分子量 | The protein has a predicted molecular mass of 32.3 kDa after removal of the signal peptide. |
| 纯度 | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| 标签 | C-Human Fc tag |
| 有无偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 货期 | In Stock |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 应用范围 | Research use only |
Figure 1. Human HCRTR2 Protein, hFc Tag on SDS-PAGE under reducing condition.
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人HCRTR2重组蛋白/Human HCRTR2 Protein, hFc Tag
￥630 - 3160
