人F2RL2重组蛋白/Human F2RL2 Protein, hFc Tag

人F2RL2重组蛋白/Human F2RL2 Protein

, hFc Tag
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  • ¥706 - 3699
  • DIMA BIOTECH/缔码生物
  • 武汉
  • PME101911
  • 2025年12月05日
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    • 详细信息
    • 技术资料
    • 保存条件

      Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    • 保质期

      12个月

    • 英文名

      Recombinant human F2RL2 Protein with C-terminal human Fc tag

    • 库存

      In Stock

    • 供应商

      缔码生物(武汉)科技有限公司

    • 规格

      10μg/50μg/100μg

    规格:10μg产品价格:¥706.0
    规格:50μg产品价格:¥2500.0
    规格:100μg产品价格:¥3699.0
    产品类型 ECD Proteins
    靶点 F2RL2
    Uniprot ID O00254
    别名 F2RL2, PAR3, Protease-activated receptor 3, Thrombin receptor-like 2, Coagulation factor II receptor-like 2
    背景 F2RL2 (Protease-activated receptor 3, PAR3) is a G-protein coupled receptor (GPCR) activated by thrombin and other proteases. It primarily couples to Gq/11 and Gi proteins, initiating phospholipase C activation, intracellular Ca²⁺ mobilization, and MAPK signaling. F2RL2 is expressed in platelets, endothelial cells, and vascular smooth muscle, where it participates in hemostasis, platelet activation, vascular inflammation, and thrombosis. Dysregulation of F2RL2 signaling is linked to coagulation disorders and cardiovascular diseases, making it a potential therapeutic target in thrombosis and vascular pathology.
    产品英文名称 Recombinant human F2RL2 Protein with C-terminal human Fc tag
    分子结构 F2RL2(Thr39-Thr94) hFc(Glu99-Ala330)
    分子量 The protein has a predicted molecular mass of 32.2 kDa after removal of the signal peptide.
    纯度 The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
    标签 C-Human Fc tag
    有无偶联 Unconjugated
    表达宿主 HEK293
    组分 Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
    货期 In Stock
    储存与运输 Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    应用范围 Research use only
    pme101911-f2rl2-sp1.png
    Figure 1. Human F2RL2 Protein, hFc Tag on SDS-PAGE under reducing condition.

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    ¥706 - 3699