GFAP Antibody (RPE)抗体，orb15053

产品描述：Mouse monoclonal to GFAP (RPE). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia..

别名:GFAP, Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, GFAPL, DKFZp459C0729, MGC139638, FLJ45472, AI836096

免疫原：Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse

克隆性:N206A/8 (Formerly sold as S206A-8)

分子量:50kDa

应用稀释比例：WB (1:1000)

应用注释：1 µg/ml of SMC-441 was sufficient for detection of GFAP in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

防腐剂:95.46mM Phosphate, 2.48mM MES and 2mM EDTA

纯化:Protein G Purified

保存说明:Conjugated antibodies should be stored according to the product label

NCBI:NP_001124491.1

Entrez:2670

UniProt ID:P14136

Note:For research use only.