Nav1.8 Antibody (HRP)抗体，orb148

产品描述：Mouse monoclonal to Nav1 (HRP). 8. Nav1. 8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1. 8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1. 8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals..

别名:Nav1.8, SCN10A, Scn10a, PN3, mPN3, Sns, SNS, Peripheral nerve sodium channel 3, Pn3 (gene name), Sensory neuron sodium channel, Sodium channel protein type 10 subunit alpha, Sodium channel protein type X alpha subunit, Voltage-gated sodium channel alpha subunit Nav1.8

免疫原：Fusion protein amino acids 1724-1956 of rat Nav1.8

克隆性:S134

分子量:220kDa

应用稀释比例：WB (1:1000), IHC (1:1000), ICC/IF (1:100)

应用注释：1 µg/ml of SMC-342 was sufficient for detection of Nav1.8 in 10 µg of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

防腐剂:73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide 0.23mM Citrate

纯化:Protein G Purified

保存说明:Conjugated antibodies should be stored according to the product label

NCBI:NP_058943.1

Entrez:29571

UniProt ID:Q62968

Note:For research use only.