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- Bioss
- bs-19383R-BF680
- 2026年10月17日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-19383R-BF680 |
| 英文名称 | SAP18 Rabbit pAb, BF680 conjugated |
| 中文名称 | BF680标记的组蛋白去乙酰化酶复合亚基SAP18抗体 |
| 英文别名 | 18 kDa Sin3-associated polypeptide; 2HOR0202; Cell growth-inhibiting gene 38 protein; Histone deacetylase complex subunit SAP18; SAP18; SAP18_HUMAN; Sin3-associated polypeptide p18. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SAP18 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > RNAi > Argonaute and Piwi |
| 亚基 | Found in a mRNA splicing-dependent exon junction complex (EJC). Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. For the ASAP complex, the association of SAP18 seems to require a preformed RNPS1:ACIN1 complex. Forms a complex with SIN3A and HDAC1. Interacts with SUFU. |
| 亚细胞定位 | Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. |
| 组织特异性 | Ubiquitous. |
| 相似性 | Belongs to the SAP18 family. |
| 功能 | Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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SAP18 Rabbit pAb, BF680 conj.(bs-19383R-BF680)-100ul
￥2980
