- ￥2980
- Bioss
- bs-19362R-Cy3
- 2026年10月17日
企业认证
相关产品推荐更多 >
SMAD3 (p-S423/S425) Rabbit pAb, Cy5 conj.(bs-3425R-Cy5)-100ul
￥2980
MAGEA10 | MAGE10 Rabbit pAb, HRP conj.(bs-6816R-HRP)-100ul
￥2980
Mouse anti-Rabbit IgM pAb, Bio conj.(bs-0369M-Bio)-100ul/1ml
￥240
HEG1 Rabbit pAb, Cy5 conj.(bs-15449R-Cy5)-100ul
￥2980
PVR | CD155 Rabbit pAb, APC conj.(bs-2525R-APC)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
源叶生物 十万种现货试剂速发，品质稳、品类全，实验不再等！Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧- 详细信息
- 技术资料
- 规格：
100ul
| 产品编号 | bs-19362R-Cy3 |
| 英文名称 | SACM1L Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的肌动蛋白抑制因子1抗体 |
| 英文别名 | Phosphatidylinositide phosphatase SAC1; SAC1; SAC1 suppressor of actin mutations 1-like(yeast); SAC1_HUMAN; SACM1L; suppressor of actin 1; Suppressor of actin mutations 1-like protein. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SACM1L |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Lipid Signaling > Lipid Phosphatases |
| 亚细胞定位 | Endoplasmic reticulum membrane. |
| 组织特异性 | Detected in heart, brain, lung, liver, kidney, pancreas and testis. |
| 相似性 | Contains 1 SAC domain. |
| 功能 | Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P. Has low activity towards PtdIns(3,5)P2. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The Saccharomyces cerevisiae SAC1 gene modulates yeast actin function and alleviates the essential requirement for phosphatidylinositol transfer protein (sec14p) activity in Golgi secretory function. The SAC1 gene product (Sac1p) is an integral membrane lipid phosphatase of the endoplasmic reticulum (ER) and the Golgi complex and contains a Sac phosphatase domain (1-2). Sac1p functions in a wide range of cellular processes including inositol metabolism, actin cytoskeletal organization, endoplasmic reticulum ATP transport, phosphatidylinositol-phospha-tidylcholine transfer protein function and multiple-drug sensitivity (3). Sac1p is an important regulator of microsomal ATP transport, providing a link between inositol phospholipid signaling and ATP-dependent processes in the yeast ER (4). Defects in Sac1p relieves the requirement for Sec14p by altering phospholipid metabolism to expand the pool of diacylglycerol in the Golgi (5). Sac1p dysfunction exerts its pleiotropic effects on yeast Golgi function, the organization of the actin cytoskeleton, and the cellular requirement for inositol, through altered metabolism of inositol glycerophospholipids (6). These effects suggest the secretory and cytoskeletal activities are coordinated to achieve proper spatial regulation of secretion in S. cerevisiae (7). |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
SACM1L Rabbit pAb, Cy3 conj.(bs-19362R-Cy3)-100ul
￥2980
