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- Bioss
- bs-13494R-BF405
- 2026年10月17日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-13494R-BF405 |
| 英文名称 | GOT1L1 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的谷氨酸草酰乙酸转氨酶1样蛋白1抗体 |
| 英文别名 | AATC2_HUMAN; cytoplasmic 2; Glutamate oxaloacetate transaminase 1-like protein 1; Glutamic oxaloacetic transaminase 1 like 1; GOT1L1; Putative aspartate aminotransferase; Putative aspartate aminotransferase, cytoplasmic 2; Transaminase A-like protein 1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GOT1L1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Homodimer (By similarity). |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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GOT1L1 Rabbit pAb, BF405 conj.(bs-13494R-BF405)-100ul
￥2980
