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GOLGA3 Rabbit pAb, APC conjuga

ted(bs-13480R-APC)-100ul
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  • ¥2980
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  • bs-13480R-APC
  • 2025年12月01日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-13480R-APC
    英文名称GOLGA3 Rabbit pAb, APC conjugated
    中文名称APC标记的高尔基体膜相关蛋白抗体
    英文别名GCP170; GOLGA 3; GOLGA3; Golgi autoantigen; Golgi complex associated protein of 170 kDa; Golgi complex-associated protein of 170 kD; Golgi membrane associated protein; Golgi peripheral membrane protein; Golgin 160; Golgin subfamily a 3; HGNC:4426; Male enhanced antigen 2; MEA2; SY2/SY10 protein; GOGA3_HUMAN.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GOLGA3/Golgin 160
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Golgi Proteins

    亚基Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not.
    亚细胞定位Cytoplasmic and Golgi Apparatus.
    组织特异性Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
    翻译后修饰Cleaved by caspases in apoptotic cells.
    功能GOLGA3 is a member of the golgin family of proteins which are localized to the Golgi. It has been postulated to play a role in nuclear transport and Golgi apparatus localization.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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    图标文献和实验
    相关实验
    • Fluorochrome Absorption and Emission Spectra

      light at 488 nm for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes

    • Fluorochrome Absorption and Emission

      for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes are useful in experiments

    • 抗癌药物的自述

      区、1个IgC样区、1个跨膜疏水区和1个由30个氨基酸组成的胞内区。不同于其他B7家族分子的是,它具有负向调节免疫应答的作用。PD-1和PD-L1是一对共抑制分子[3]。 这对共抑制分子,对癌细胞是如何发挥作用的呢。 憋急,听我慢慢道来! 人类身体健康的卫士「T细胞」的活化是需要接收「双重信号」的:首先,T细胞表面受体(TCR)识别由抗原提呈细胞(APCs)提呈的抗原肽,使T细胞初步活化;然后,APC表面的共刺激分子与T细胞表面的相应共刺激分子结合,使T

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