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- bs-13468R-BF594
- 2025年12月01日
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100ul
| 产品编号 | bs-13468R-BF594 |
| 英文名称 | GNG13 Rabbit pAb, BF594 conjugated |
| 中文名称 | BF594标记的G蛋白γ13/Gγ13 抗体 |
| 英文别名 | G gamma subunit, clone:h2 35; G(gamma)13; GBG13_HUMAN; Gng13; Guanine nucleotide binding protein 13; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; h2 35. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GNG13 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > G Protein Signaling > Heterotrimeric G Proteins > G Proteins |
| 亚基 | G proteins are composed of 3 units, alpha, beta and gamma. |
| 亚细胞定位 | Cell membrane. |
| 相似性 | Belongs to the G protein gamma family. |
| 功能 | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alhfa, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the beta gamma delta subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the gamma as well as the alhfa and beta subunits, and that preferential associations between members of subunit families increase G protein functional diversity. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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GNG13 Rabbit pAb, BF594 conjugated(bs-13468R-BF594)-100ul
￥2980
