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- Bioss
- bs-2794R-PE
- 2025年12月01日
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100ul
| 产品编号 | bs-2794R-PE |
| 英文名称 | RGS5 Rabbit pAb, PE conjugated |
| 中文名称 | PE标记的G蛋白信号转导调节因子5抗体 |
| 英文别名 | MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; Regulator of G Protein Signalling 5; RGS 5; RGS5_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse RGS5 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Angiogenic Factors Cardiovascular > Blood > Blood Pressure regulation Cardiovascular > Heart > Hypertrophy Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚细胞定位 | Isoform 1: Cytoplasm，Membrane. Isoform 2: Cytoplasm. |
| 相似性 | Contains 1 RGS domain. |
| 功能 | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi and Gq class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. RGS5 seems to be an important signalling regulator in the vascular system. Present data suggest that RGS5 may be involved in the regulation of capillary growth, angiogenesis, and in the pathophysiology of stroke. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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RGS5 Rabbit pAb, PE conjugated(bs-2794R-PE)-100ul
￥2980
