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- bs-2665R-PacificBlue
- 2025年12月01日
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100ul
| 产品编号 | bs-2665R-PacificBlue |
| 英文名称 | Regucalcin Rabbit pAb, Pacific Blue conjugated |
| 中文名称 | Pacific Blue标记的衰老标记蛋白30抗体 |
| 英文别名 | Gluconolactonase; GNL; RC; Regucalcin; RGN; RGN_HUMAN; Senescence marker protein 30; SMP 30; SMP-30. |
| 产品应用 | IF=1:100-500, Flow-Cyt=1ug/test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Regucalcin |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins |
| 亚基 | Monomer. |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Belongs to the SMP-30/CGR1 family. |
| 功能 | Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Regucalcin is a Ca2+ binding protein that is encoded by a highly conserved gene in vertebrate species. Regucalcin is greatly expressed in liver and kidney cortex, and the expression is mediated through a Ca2+ signaling mechanism with AP1 and NFI-A1 as transcriptional factors. It plays a multifunctional role as a regulatory protein in intracellular signaling processes in the cytoplasm and nucleus of cells including the maintenance of intracellular Ca2+ homeostasis, the regulation of various Ca2+ dependent protein kinases and tyrosine kinases, protein phosphatases, nitric oxide (NO) synthase, and the suppression of nuclear DNA and RNA syntheses. Regucalcin has suppressive effects on cell proliferation, cell death and apoptosis, and is suggested to play a physiologic role in the maintenance of cellular homeostasis. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
| {Flow-Cyt} | {1ug/test} |
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Regucalcin Rabbit pAb, Pacific Blue conjugated(bs-2665R-PacificBlue)-100ul
￥2980
