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RBM25 Rabbit pAb, APC-Cy7 conj

ugated(bs-19768R-APC-Cy7)-100ul
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  • bs-19768R-APC-Cy7
  • 2025年12月01日
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      100ul

    产品编号bs-19768R-APC-Cy7
    英文名称RBM25 Rabbit pAb, APC-Cy7 conjugated
    中文名称APC-Cy7标记的RNA结合蛋白25抗体
    英文别名Arg/Glu/Asp rich protein, 120 kDa; Arg/Glu/Asp-rich protein of 120 kDa; fSAP94; functional spliceosome-associated protein 94; NET52; Protein S164; Rbm25; RBM25_HUMAN; RED120; RNA binding motif protein 25; RNA binding region(RNP1, RRM) containing 7; RNA-binding motif protein 25; RNA-binding protein 25; RNA-binding region-containing protein 7; RNPC7; S164; Snu71; U1 small nuclear ribonucleoprotein 1SNRP homolog.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human RBM25
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing

    亚细胞定位Nucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.
    翻译后修饰Sumoylated.
    相似性Contains 1 PWI domain.
    Contains 1 RRM (RNA recognition motif) domain.
    功能RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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    图标文献和实验
    相关实验

    • Fluorochrome Absorption and Emission Spectra

      light at 488 nm for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes

    • Fluorochrome Absorption and Emission

      for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes are useful in experiments

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    RBM25 Rabbit pAb, APC-Cy7 conjugated(bs-19768R-APC-Cy7)-100ul
    ￥2980