Ki-67 Recombinant Rabbit mAb, BF680 conjugated(bsm-52455R-BF680)-100ul

Ki-67 Recombinant Rabbit mAb,

BF680 conjugated(bsm-52455R-BF680)-100ul
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  • ¥3200
  • Bioss已认证
  • bsm-52455R-BF680
  • 2025年12月01日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bsm-52455R-BF680
    英文名称Ki-67 Recombinant Rabbit mAb, BF680 conjugated
    中文名称BF680标记的Ki67重组兔单抗
    英文别名Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.
    产品应用IF=1:200-1000, ICC/IF=1:200-1000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Ki67
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell cycle > Cell division

    Cancer > Tumor biomarkers

    Cell Biology > Cell Cycle > Markers

    Neuroscience > Cell Type Marker > Neuron marker > Soma marker

    Neuroscience > Neurology process > Neurogenesis

    Tags & Cell Markers > Cell Type Markers > Replication

    亚细胞定位Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes.
    相似性Contains 1 FHA domain.
    功能Thought to be required for maintaining cell proliferation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

     

    应用推荐稀释比例
    {IF}{1:200-1000}
    {ICC/IF}{1:200-1000}

     

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