- ￥3200
- Bioss
- bsm-60788R-Cy5
- 2025年12月01日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
phospho-NFKB1 (Ser927) Rabbit pAb, PerCP-Cy7 conjugated(bs-3300R-PerCP-Cy7)-100ul
￥2980CGRP1 Rabbit pAb, Biotin conjugated(bs-42251R-Bio)-100ul
￥2980TNFSF13B Rabbit pAb, PerCP-Cy7 conjugated(bs-43649R-PerCP-Cy7)-100ul
￥2980
MEF2B Rabbit pAb, APC-Cy7 conjugated(bs-9470R-APC-Cy7)-100ul
￥2980
phospho-DAXX (Ser517) Rabbit pAb, BF750 conjugated(bs-5292R-BF750)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bsm-60788R-Cy5 |
| 英文名称 | SOX2 Recombinant Rabbit mAb, Cy5 conjugated |
| 中文名称 | Cy5标记的胚胎干细胞关键蛋白重组兔单克隆抗体 |
| 英文别名 | transcriptional factor SOX2; ANOP3; cb236; delta EF2a; lcc; MCOPS3; MGC148683; MGC2413; RGD1565646; Sex determining region Y box 2; Sex determining region Y-box 2; SOX 2; SRY(sex determining region Y) box 2; SRY box containing gene 2; SRY related HMG box 2; SRY related HMG box gene 2; SRY-box 2; ysb; SOX2_HUMAN; Transcription factor SOX-2; SOX2_HUMAN. |
| 产品应用 | IF=1:200-800 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SOX2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 浓度 | 1mg/ml |
| 储存液 | PBS, Glycerol, BSA. |
| 研究领域 | Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules Developmental Biology > Reproduction > Germ cell markers Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > Leucine Zipper Epigenetics and Nuclear Signaling > Transcription > Domain Families > HMG Box Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Neurology process > Neurogenesis Stem Cells > Embryonic Stem Cells > Intracellular Stem Cells > Germline Stem Cells > Embryonic Germ Cells |
| 亚基 | Interacts with ZSCAN10. Interacts with SOX3 and FGFR1. |
| 亚细胞定位 | Nucleus. |
| 翻译后修饰 | Sumoylation inhibits binding on DNA and negatively regulates the FGF4 transactivation. |
| 相似性 | Contains 1 HMG box DNA-binding domain. |
| 功能 | Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:200-800} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
