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- bsm-61128R-BF680
- 2025年12月01日
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100ul
| 产品编号 | bsm-61128R-BF680 |
| 英文名称 | HSP90 beta Recombinant Rabbit mAb, BF680 conjugated |
| 中文名称 | BF680标记的热休克蛋白90β/HSP90 β 重组兔单抗 |
| 英文别名 | HS90B; HSP 84; HSP90-beta; HSP90AB1; HSPC2; HSPCB; Heat shock protein HSP 90-beta. |
| 产品应用 | IF=1:100-500, Flow-Cyt=1ug/Test, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human Hsp90 beta |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins |
| 亚基 | Homodimer. Interacts with p53/TP53. Forms a complex with CDK6 and Hsp90/HSP90AB1. Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer. Interacts with CHORDC1 and DNAJC7. Interacts with FKBP4. |
| 亚细胞定位 | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| 翻译后修饰 | Ubiquitinated in the presence of STUB1-UBE2D1 complex (in vitro).
ISGylated. S-nitrosylated; negatively regulates the ATPase activity (Probable). |
| 相似性 | Belongs to the heat shock protein 90 family. |
| 功能 | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
| {Flow-Cyt} | {1ug/Test} |
| {ICC/IF} | {1:100-500} |
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HSP90 beta Recombinant Rabbit mAb, BF680 conjugated(bsm-61128R-BF680)-100ul
￥3200
