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- bs-41320R-PE-Cy5
- 2025年12月01日
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100ul
| 产品编号 | bs-41320R-PE-Cy5 |
| 英文名称 | TLR7 Rabbit pAb, PE-Cy5 conjugated |
| 中文名称 | PE-Cy5标记的Toll样受体7抗体 |
| 英文别名 | TLR-7; PRO285; TLR 7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant human TLR7 protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Immunology > Immunoglobulins > Receptors Immunology > Innate Immunity > Macrophage / Inflamm. Immunology > Innate Immunity > TLR Signaling Signal Transduction > Adapters > Transmembrane |
| 亚基 | Interacts with MYD88 via their respective TIR domains. Interacts with UNC93B1. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. |
| 组织特异性 | Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells. |
| 相似性 | Belongs to the Toll-like receptor family. Contains 27 LRR (leucine-rich) repeats. Contains 1 TIR domain. |
| 功能 | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
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TLR7 Rabbit pAb, PE-Cy5 conjugated(bs-41320R-PE-Cy5)-100ul
￥2980
