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- bsm-61558R-BF350
- 2025年12月01日
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100ul
| 产品编号 | bsm-61558R-BF350 |
| 英文名称 | TXNRD1 Recombinant Rabbit mAb, BF350 conjugated |
| 中文名称 | BF350标记的硫氧环蛋白还原酶1重组兔单抗 |
| 英文别名 | GRIM12; KDRF; KM 102 derived reductase like factor; xidoreductase; Thioredoxin reductase 1; TR1; TRXR1; TXNR; TXNRD. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human TR |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Homodimer. Isoform 4 interacts with ESR1 and ESR2. Interacts with HERC5. |
| 亚细胞定位 | Cytoplasm. Isoform 4: Cytoplasm. Nucleus. Isoform 5: Cytoplasm. |
| 组织特异性 | Isoform 1 is expressed predominantly in Leydig cells (at protein level). Also expressed in ovary, spleen, heart, liver, kidney and pancreas and in a number of cancer cell lines. Isoform 4 is widely expressed with highest levels in kidney, testis, uterus, ovary, prostate, placenta and fetal liver. |
| 翻译后修饰 | The N-terminus of isoform 5 is blocked. ISGylated (Probable). |
| 相似性 | Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. Contains 1 glutaredoxin domain. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. Contains a selenocysteine residue at the C-terminal active site that is essential for catalysis (Probable). Also has reductase activity on hydrogen peroxide (H2O2). |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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TXNRD1 Recombinant Rabbit mAb, BF350 conjugated(bsm-61558R-BF350)-100ul
￥2980
