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- bsm-62846R-PerCP
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100ul
| 产品编号 | bsm-62846R-PerCP |
| 英文名称 | Integrin Alpha V Recombinant Rabbit mAb, PerCP conjugated |
| 中文名称 | PerCP标记的整合素αV（CD51）重组兔单抗 |
| 英文别名 | CD51; Integrin alpha five; Integrin alpha-V light chain; ITGAV; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR. |
| 产品应用 | IF=1:200-800 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human Integrin alpha V |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Adhesion / ECM > Integrins Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Integrins Cardiovascular > Blood > Platelets Microbiology > Interspecies Interaction > Host Virus Interaction Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage |
| 亚基 | Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this viru. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. Interacts with RAB25. |
| 亚细胞定位 | Cell Membrane |
| 相似性 | Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. |
| 功能 | The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:200-800} |
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文献和实验High‐Throughput, Multiplexed Analysis of 3‐Nitrotyrosine in Individual Proteins
.1 ) Phosphate‐buffered saline (PBS; Fisher Scientific) Alexa Fluor 546–conjugated goat anti—rabbit IgG (Invitrogen, cat. no. A‐11035
Methods to Detect Protein Glutathionylation
mouse monoclonal primary antibody (ViroGen), 1:100 dilution in TBS‐T containing 0.5% (w/v) nonfat dry milk Horseradish peroxidase (HRP)‐conjugated secondary antibody against mouse IgG
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
Ballard, J.L., Peeva, V.K., deSilva, C.J., Lynch, J.L., and Swanson, N.R., 2007. Comparison of Alexa Fluor and CyDye for practical DNA microarray use. Mol. Biotechnol. 36:175‐183.
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