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- bsm-43172R-BF350
- 2025年12月01日
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100ul
| 产品编号 | bsm-43172R-BF350 |
| 英文名称 | Human CG beta Recombinant Rabbit mAb, BF350 conjugated |
| 中文名称 | BF350标记的人绒毛膜促性腺激素β重组兔单抗 |
| 英文别名 | CGB5; CGB8; CGB3_HUMAN;Choriogonadotropin subunit beta (CG-beta); Chorionic gonadotropin chain beta, Choriogonadotropin subunit beta 3 |
| 产品应用 | IF=1:200-800 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant human Choriogonadotropin subunit beta 3 protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in placenta, testis and pituitary. |
| 相似性 | Belongs to the glycoprotein hormones subunit alpha family. |
| 功能 | Encoded by a cluster of genes that have evolved by duplication from LHB. HCG-beta is encoded by six non-allelic genes (CGB) clustered on chromosome 19q13.3 and named CGB1, CGB2, CGB3, CGB5, CGB7 and CGB8. Two specific hCGb proteins that differ by three amino acids in positions 2,4 and 117 have been described: type 1 (CGB7) and type 2 (CGB3, CGB5, CGB8). The CGB gene first arose in the common ancestor of the anthropoid primates. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB1 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 155 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:200-800} |
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