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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
储存条件:-20℃,干燥、避光、密封
- 保质期:
2年
- 英文名:
DNA relaxation-IN-1
- 库存:
1000
- 供应商:
四川省维克奇生物科技有限公司
- CAS号:
2190506-29-5
- 规格:
5mg
英文名称:DNA relaxation-IN-1
分子式:C30H27N3O2S
CAS:2190506-29-5
储存条件:-20℃,干燥、避光、密封
规格:5mg10mg20mg50mg100mg500mg1g80g等应客户需求包装
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文献和实验Assaying DNA Topoisomerase I Relaxation Activity
Type I topoisomerases catalyze topological changes in duplex DNA by reversibly nicking one strand, whereas type II enzymes catalyze the transient breakage of both strands simultaneously. The type I enzymes alter the linking number
Topoisomerase II-Catalyzed Relaxation and Catenation of Plasmid DNA
- or intermolecular. The enzyme relaxes supercoiled DNA in an intramolecular reaction, while it catenates and decatenates closed circular DNA in an intramolecular reaction (1 ,5 ). This chapter describes the relaxation and catenation reactions of topoisomerase II.
Several biochemical and biophysical methods are available to study the intercalation of a small molecule between two consecutive base pairs of DNA. Among them, the topoisomerase I-mediated DNA relaxation assay has proved highly efficient
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