生长因子受体结合蛋白2抗体

生长因子受体结合蛋白2抗体产品类别

兔抗人、大、小鼠Grb2蛋白抗体

产品价格

0.2ml/890元

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

生长因子受体结合蛋白2抗体产品介绍

Growth factor receptor bound protein 2 (GRB2), also known as Ash protein, is a 24 kDa protein that contains a central Src homology (SH2) domain flanked by two SH3 domains. GRB2 is believed to be a regulatory subunit of signaling molecules whose activity is modulated by receptor binding. GRB2 associates with activated (tyrosine phosphorylated) EGFR and PDGFR via its SH2 domain as well as IRS1, SHC, and LNK through SH2 and SH3 domains. The SH3 domain binds to SOS, a guanine nucleotide exchange factor for Ras proteins. Endocytosis of activated EGFR requires the interaction of GRB2 with the GTP binding protein dynamin, a factor essential to the formation of endocytotic vesicle. It is ubiquitously expressed and several isoforms are produced by alternative splicing. On SDS PAGE, GRB2 has an apparent molecular weight of 28 kDa.
Also known as:
Growth factor receptor-bound protein 2; Abundant SRC homology; Adapter protein GRB2; ASH; Ash protein; EGFRBP GRB2; Epidermal growth factor receptor binding protein; Epidermal growth factor receptor binding protein GRB2; GRB 2; GRB2 adapter protein; Grb3 3; Growth Factor Receptor Bound Protein 2; Growth factor receptor bound protein 3; HT027; MST084; MSTP084; OTTHUMP00000166096; OTTHUMP00000166097; OTTHUMP00000166098; Protein ASH; SEM5 ; SH2/SH3 adapter GRB2.zk-1937R Zyxin斑联蛋白抗体
zk-1939R ZNF474锌指蛋白474抗体
zk-13554R ZBED4锌指蛋白BED4抗体
zk-1938R ZW10 peptide着丝粒蛋白抗体
zk-0275R ZNF231锌指蛋白231抗体
zk-9189R ZNF354C锌指蛋白354C抗体
zk-12148R ZNF312锌指蛋白312抗体
zk-0625R ZNF268锌指脂蛋白抗体
zk-0627R ZNF268锌指脂蛋白-1c抗体
zk-12147R ZIC5锌指蛋白ZIC5抗体
zk-7580R ZFAND5AN1型锌指蛋白5抗体
zk-7581R ZHX2甲胎蛋白调节蛋白1抗体
zk-7677R ZDHHC16细胞凋亡调控蛋白ZDHHC16抗体
zk-6347R Zinc finger protein 754锌指蛋白754抗体
zk-11777R ZFYVE27锌指FYVE结构域蛋白27抗体
zk-13549R ZAR1受精卵抑制蛋白1抗体
zk-8447R ZNF471锌指蛋白471抗体
zk-4229R ZDHHC21γ-氨基丁酸A受体相关膜蛋白3
zk-13563R ZBTB1锌指蛋白909抗体
zk-7092R ZNF420锌指蛋白420抗体
zk-7093R ZNHIT1细胞周期蛋白1结合蛋白抗体
zk-11414R ZNF318锌指蛋白318抗体
zk-12208R ZNF281锌指蛋白281抗体
zk-12209R ZNF274锌指蛋白274抗体
zk-12210R ZNF81锌指蛋白81抗体
zk-12211R ZNF148锌指蛋白148抗体
zk-12212R ZNF342锌指蛋白342抗体
zk-12213R ZNF350锌指蛋白350/乳腺癌易感基因1结合蛋白抗体
zk-12217R ZNF263锌指蛋白263抗体
生长因子受体结合蛋白2抗体