Human IL-17 ELISA kit

Human IL-17 ELISA kit

Catalog No.: IRKTAH3063

$455
Category: Assay and ELISA Kits

Product Description

Human IL-17 ELISA Kit

Our Human IL-17 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human IL-17 in cell culture supernates, serum and plasma (heparin, EDTA).

IL-17 is an inflammatory cytokine produced primarily by a unique lineage of CD4 T cells that plays critical roles in the pathogenesis of multiple autoimmune diseases. Interleukin-17 is expressed by activated T cells and is 57% identical to the 17- to 26-kD secretory glycoprotein encoded by gene 13 of the herpesvirus saimiri(HVS-13). IL17 induces nuclear factor kappa-B and the expression of IL6, intercellular adhesion molecule-1, granulocyte macrophage colony-stimulating factor,and prostaglandin E2, as well as the maturation of CD34 positive hematopoietic precursors into neutrophils. Anti-IL17 antibodies significantly inhibited osteoclast formation induced by culture media of RA synovial tissues. The standard product used in this kit is recombinant human IL-17, consisting of 136 amino acids with the molecular mass of 16KDa.

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