Mouse TGF-beta 2 ELISA Kit

Mouse TGF-beta 2 ELISA Kit

Catalog No.: IRKTAH5449

$495
Category: Assay and ELISA Kits

Product Description

Mouse TGF-beta 2 ELISA Kit - 1 Kit (96 Wells)

Our Mouse TGF-beta 2 ELISA Kit is a sandwich ELISA intended for the quantitative determination of activated mouse TGF-beta 2 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured human anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.

Related Products

• Innovative Grade US Origin Mouse Plasma - CD-1

  From $85 to $2395

• Innovative Grade US Origin CD-1 Mouse Serum

  From $85 to $2395