配对盒基因5抗体

配对盒基因5抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

配对盒基因5抗体产品介绍

同源结构域蛋白（Homeodomain Proteins）
PAX-5属于转录抑制因子。在胚胎发育和肿瘤生长中起关键作用。其突变和某些肿瘤的发病有关。
The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
PAX5 expression is not only continuously required for B cell lineage commitment during early B cell development but also for B lineage maintenance. PAX5 is found in most cases of mature and precursor B cell non-Hodgkin lymphomas/leukemias. Pax-5 is not detected in Multiple myeloma and solitary plasmacytoma cell lymphomas do express Pax5 except for those with terminal B cell differentiation. T cell neoplasms do not stain with anti-Pax5; however there is a strong association with CD20 expression.zkm-2741M Hepatocyte(2H5)人肝细胞单克隆抗体/肝细胞特异性抗原抗体
zkm-0287M His tag(2D5)小鼠抗聚组氨酸单克隆抗体
zk-8870R Hepcidin-25铁调节蛋白/铁调素抗体
zk-7233R HSJ1热休克蛋白J1抗体
zk-3767R Hes5发状分裂相关增强子-5抗体
zk-3181R Phospho-HSP90 alpha (Thr5 + Thr7)磷酸化热休克蛋白90α抗体
zk-3185R Phospho-Histone H2A.X (Ser139)磷酸化组蛋白H2AX抗体
zk-3187R Phospho-Histone H3 (Ser28)磷酸化组蛋白H3抗体
zk-3188R Phospho-Histone H3 (Thr11)磷酸化组蛋白H3抗体
zk-3189R Phospho-Histone H3 (Thr3)磷酸化组蛋白H3抗体
zk-2810R HDAC5组蛋白去乙酰化酶5抗体
zk-2284R H5N1 HemagglutininA型流感病毒H5N1凝集素
zk-2274R HCMV UL49人巨细胞病毒UL49蛋白抗体
zk-8617R HNF1 beta肝细胞核因子1β/HNF-1β抗体
zk-15479R HHLA3HHLA3蛋白抗体
zk-15477R HHIPL2HHIP样蛋白2抗体
zk-10331R H3N2 Matrix Protein 2A型流感病毒H3N2-M2蛋白抗体
zk-13643R HSH2DHSH2D抗体
zk-4561R Hirudin水蛭素抗体
zk-10086R HLA Class 1 ABC白细胞抗原A抗体
zk-10202R HPV16 E7人乳头瘤病毒16型E7抗体
zk-10201R HPV58 E6人类乳头状瘤病毒58 E6蛋白抗体
zkm-0990M HPV16 E6 protein人类乳头状瘤病毒16抗体
zk-10204R HPV18 E7人类乳头状瘤病毒18 E7抗体
zk-10203R HPV31 E7人类乳头状瘤病毒31 E7抗体
zk-12383R HES2转录因子HES2抗体
配对盒基因5抗体