Human ESM1/Endocan ELISA Kit

Human ESM1/Endocan ELISA Kit

Catalog No.: IRKTAH5101

$465
Category: Assay and ELISA Kits

Product Description

Human ESM1/Endocan ELISA Kit - 1 Kit (96 Wells)

Our Human ESM1/Endocan ELISA Kit is a sandwich ELISA intended for the quantitative determination of human ESM1 in cell culture supernates, serum and plasma (heparin, EDTA).

Endothelial cell-specific molecule 1, also known as Endocan, is a protein that in humans is encoded by the ESM1 gene. This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis by independent teams. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF(vascular endothelial growth factor) or FGF-2 (fibroblast growth factor 2).

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