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- 详细信息
- 技术资料
- 供应商:
再康生物
- 库存:
50
- 规格:
96 tests
Human Rage ELISA Kit
Catalog No.: IRKTAH5220
$565
Category: Assay and ELISA Kits
Product Description
Human Rage ELISA Kit - 1 Kit (96 Wells)
Our Human Rage ELISA Kit is a sandwich ELISA intended for the quantitative determination of human Rage in cell culture supernates, serum and plasma (heparin, EDTA).RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as AGER. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB).
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