- 询价
- R&D
- ZK-0101727
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- cMOAT/MRP2 (M2I-4) Monoclonal Antibody (SIGNET)详细信息：
-
Description Monoclonal antibody against cMOAT/MRP2 (clone M2I-4) Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone M2I-4 Form Tissue Culture Supernatant (0.1% NaN3 + 0.7% BSA) Host Mouse IsoType cMOAT/MRP2 (M2I-4) Monoclonal Antibody (SIGNET)IgG1 Specificity Covances clone M2I-4 reacts with an internal epitope of cMOAT/MRP2. Overexpression of cMOAT/MRP2 has been observed in a subset of cisplatin resistant cell lines. Clone M2I-4 does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.
This antibody was generated against a bacterial fusion protein of cMOAT/MRP2 containing amino acids 215-310.Uses This antibody is effective in immunohistochemistry (IHC). Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - IHC: ≥1:20 with biotin based detection systems such as USA Ultra Streptavidin Detection (SIG-32250).
Tissue Sections: Formalin-fixed, paraffin-embedded tissues
Pretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as citrate buffer retrieval solution (SIG-31932).
Incubation: 20-60 minutes at room temperature.
Notes Positive tissue: Liver Storage cMOAT/MRP2 (M2I-4) Monoclonal Antibody (SIGNET) References Scheffer GL. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5 and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res 60(18):5269-77, 2000.
Kool M, et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5 homologs of the multidrug resistance-associated protein gene (MRP1) in human cancer cell lines. Cancer Res 57:3537-3547, 1997.
Paulusma CC, et al. Congenital jaundice in rats with a mutation in a multidrug resistance associated protein gene. Science 271:1126-1128, 1996.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - IHC: ≥1:20 with biotin based detection systems such as USA Ultra Streptavidin Detection (SIG-32250).
- cMOAT/MRP2 (M2I-4) Monoclonal Antibody (SIGNET)
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cMOAT/MRP2 (M2I-4) Monoclonal Antibody (SIGNET)
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