- 询价
- R&D
- ZK-0101541
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Tryptophan Hydrozklase Polyclonal Antibody保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description Polyclonal Antibody against Tryptophan Hydrozklase Form Affinity Purified Antibody (in 150 mM NaCl, 10 mM HEPES (pH 7.5), 100 µg per ml BSA and 50% glycerol) Host Sheep Species Reactivity Tryptophan Hydrozklase Polyclonal AntibodyHuman, Rat Specificity Tryptophan hydrozklase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis.
This antiserum was developed against purified recombinant rabbit tryptophan hydrozklase, isolated as inclusion bodies from E. coli. It was subsequently purified on an affinity column coupled to recombinant rabbit tryptophan hydrozklase.Uses This antibody is effective in immunoblotting and immunohistochemistry (IHC). The antibody has been used successfully with rat and human brain tissues. Based upon the relatively high degree of homology of tryptophan hydrozklase, the antibodies should cross-react with other mammalian species. Suggested Working Dilution Tryptophan Hydrozklase Polyclonal AntibodyThe optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Western blot: 1:1,000*
- Dot blot: 1:1,000
- IHC: 1:1,000
Notes *Predicted MW = 55kD Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. For long-term storage, keep the antibody at -80°C. References Haycock JW, Kumer SC, Lewis DA, Vrana KE, Stockmeier CA. A monoclonal antibody to tryptophan hydrozklase: applications and identification of the epitope. J. Neurosci. Meth. 114:205-212, 2002. Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Tryptophan Hydrozklase Polyclonal Antibody
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Tryptophan Hydrozklase Polyclonal Antibody
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