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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
来电咨询
- 克隆性:
多克隆
- 标记物:
见 说 明 书
- 宿主:
Goat,Rabbit,Mouse
- 适应物种:
人,大鼠,小鼠,兔
- 形态:
液态/粉状
- 应用范围:
科研使用
- 浓度:
1mg/1ml
- 保存条件:
-20℃保存
- DJ-1 Monoclonal Antibody保存于运输说明:
- Store at -20°C
- 详细信息:
-
Description Monoclonal Antibody against DJ1 Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone E2.19 Form DJ-1 Monoclonal AntibodyAscites Host Mouse Species Reactivity Human IsoType IgM [Ab] 3-5 mg/mL Specificity DJ1 is a conserved protein with a multifaceted function ranging from cellular transformation, control of protein-RNA interaction, to oxidative stress response to control of male infetility. The sequence of DJ1 is conserved among prokaryotic and eukaryotic cells. Mutations in DJ1 have been recently reported to be associated with recessive, early onset Parkinsons disease.
The DJ1 antibody was raised against purified full length recombinant DJ1.Uses This antibody is effective in immunoblotting and immunocytochemistry applications. Suggested Working Dilution DJ-1 Monoclonal AntibodyThe optimal working dilution should be determined for each specific assay condition. - Western blot: 1:1,000*
Notes *Predicted MW = 25kD
Predicted primary sequence mol wt is 20 kda, but actual size on the gel seems higher.Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. References Hod Y. Differential control of apoptosis by DJ1 in prostate benign and cancer cells. J Cell Biochem, 92:1221-1233, 2004.
Miller DW, Ahmad R, Hague S, Baptista MJ, Canet-Aviles R, McLendon C, Carter DM, Zhu PP, Stadler J, Chandran J, Klinefelter GR, Blackstone C, Cookson MR. L166P mutant DJ-1, causative for recessive Parkinsons disease, is degraded through the ubiquitin-proteasome system. J Biol Chem 278(38):36588-36595, 2003.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - DJ-1 Monoclonal Antibody
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