Beta Amyloid, 1-16 (6E10) Mono
clonal Antibody Low Endotoxin, Purified Exclusively Provided by Covance- 询价
- R&D
- ZK-0101172
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Beta Amyloid, 1-16 (6E10) Monoclonal Antibody Low Endotoxin, Purified Exclusively Provided by Covance保存于运输说明：
- Store at -20°C or below
- 详细信息：
-
Description Beta Amyloid (Aβ) Monoclonal Antibody, 6E10
Covance is the Exclusive Provider of this Antibody ProductIntended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone Beta Amyloid, 1-16 (6E10) Monoclonal Antibody Low Endotoxin, Purified Exclusively Provided by Covance6E10 Form Protein G Purified Antibody (in PBS; no preservatives or carrier proteins)Endotoxin level < 0.5 EU/mL Host Mouse Species Reactivity Human IsoType IgG1 [Ab] 1 mg/mL Specificity This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS). Beta amyloid forms are deposited in the CNS of patients with Alzheimer’s disease and Down’s syndrome. Covances beta amyloid antibody 6E10 reacts to the abnormally processed isoforms, as well as precursor forms. Uses This antibody is effective in immunoblotting, immunohistochemistry (IHC), immunoprecipitation (IP), and ELISA. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - IHC:
Tissue Sections: Formalin-fixed human paraffin-embedded brain sections
Pretreatment: Formic acid (70%) for 10-30 minutes at room temperature
Storage Beta Amyloid, 1-16 (6E10) Monoclonal Antibody Low Endotoxin, Purified Exclusively Provided by CovanceStore at -20°C or below. Upon initial thawing, apportion into working aliquots and store at -20°C or below. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Do not store in frost-free freezers. References Thakker DR, et al. Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice. Proc Natl Acad Sci USA Feb 25, 2009.
Klyubin I, et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med 11(5):556-61, 2005.
Oddo S, et al. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer’s disease. PNAS 102(8):3046-51, 2005.
Fratta P, et al. Mutant ubiquitin UBB+1 is accumulated in sporadic inclusion-body myositis muscle fibers. Neurology 63:1114-1117, 2004.
Funamoto S, et al. Truncated carbozkl-terminal fragments of beta- Amyloid precursor protein are processed to Amyloid beta-proteins 40 and 42. Biochem 43:13523-13540, 2004.
Herzig M, et al. Abeta is targeted to the vasculature in a mouse model of heredity cerebral hemorrhage with amyloidosis. Nat. Neuro. 7(9):954-959, 2004.
Kim KS, et al. Production and characterization of monoclonal antibodies reactive to synthetic cerebrovascular amyloid peptide. Neurosci. Res. Comm. 2:121-130, 1988.
Kim KS, et al. Neurosci. Res. Comm. 7:113, 1988.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - IHC:
- Beta Amyloid, 1-16 (6E10) Monoclonal Antibody Low Endotoxin, Purified Exclusively Provided by Covance
- zk-15096R C20orf15120号染色体开放阅读框151抗体
zk-15117R c20orf7820号染色体开放阅读框78抗体
zk-15103R C20orf18720号染色体开放阅读框187抗体
zk-15126R C21orf5921号染色体开放阅读框59抗体
zk-15097R C20orf152 20号染色体开放阅读框152抗体
zk-15098R C20orf16520号染色体开放阅读框165抗体
zk-15099R C20orf16620号染色体开放阅读框166抗体
zk-15100R C20orf17320号染色体开放阅读框173抗体
zk-15106R C20orf2420号染色体开放阅读框24抗体
zk-15109R C20orf30 20号染色体开放阅读框30抗体
zk-15111R C20orf420号染色体开放阅读框4抗体
zk-15113R C20orf720号染色体开放阅读框7抗体
zk-15118R C20orf79 20号染色体开放阅读框79抗体
zk-15119R C20orf9420号染色体开放阅读框94抗体
zk-15125R C21orf3721号染色体开放阅读框37抗体
zk-15132R C22orf15 22号染色体开放阅读框15抗体
zk-15131R C22orf1322号染色体开放阅读框13抗体
zk-15134R C22orf2622号染色体开放阅读框26抗体
zk-15142R C2b补体C2b链多肽抗体
zk-15147R C2orf162号染色体开放阅读框16抗体
zk-15148R C2orf27 2号染色体开放阅读框27抗体
zk-12989R phospho-delta 1 Catenin (Ser268)磷酸化δ连环蛋白抗体
zk-12990R phospho-delta 1 Catenin (Thr310)磷酸化δ连环蛋白抗体
zk-12991R phospho-delta 1 Catenin (Thr916)磷酸化δ连环蛋白抗体
zk-12992R phospho-delta 1 Catenin (Tyr228)磷酸化δ连环蛋白抗体
zk-12993R phospho-delta 1 Catenin (Tyr291)磷酸化δ连环蛋白抗体
zk-12994R phospho-delta 1 Catenin (Tyr96)磷酸化δ连环蛋白抗体
zk-15140R C22orf43 22号染色体开放阅读框43抗体
zk-15143R C2CD3C2CD3蛋白抗体
zk-10136R Caspase 14半胱胺酸蛋白酶蛋白14抗体
zk-15178R C3orf553号染色体开放阅读框55抗体
zk-15181R C3orf653号染色体开放阅读框65抗体
zk-15165R C3orf14 3号染色体开放阅读框14抗体
zk-15167R C3orf203号染色体开放阅读框20抗体
zk-15169R C3orf23 3号染色体开放阅读框23抗体
zk-15173R C3ORF31 3号染色体开放阅读框31抗体
zk-15174R C3orf323号染色体开放阅读框32抗体
zk-15176R C3orf363号染色体开放阅读框36抗体
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Beta Amyloid, 1-16 (6E10) Monoclonal Antibody Low Endotoxin, Purified Exclusively Provided by Covance
询价
