- 询价
- R&D
- ZK-0101023
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Tau (C3) Monoclonal Antibody, Purified (SIGNET)详细信息：
-
Description Purified Monoclonal Antibody against Human Tau
(Formerly Signet Catalog Nos: 9410-02, 9410-05, 9410-10)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone C3 Form Purified Antibody (in PBS; no preservatives or carrier proteins) Host Tau (C3) Monoclonal Antibody, Purified (SIGNET)Mouse Species Reactivity Human IsoType IgG1 [Ab] 0.5 mg/mL Specificity This antibody is specific for Tau cleaved at D421. Uses This antibody is effective in immunoblotting, immunohistochemistry (IHC) and ELISA. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. Storage Tau (C3) Monoclonal Antibody, Purified (SIGNET)Do not store antibody diluted below 50 ug/mL in the absence of protein (i.e.: add 2% bovine serum albumin). The antibody is best stored undiluted at -80°C. It is suggested that the total volume is aliquoted upon initial thaw. References Guillozet-Bongaarts AL, Garcia-Sierra F, Reynolds MR, Horowitz PM, Fu Y, Wang T, Cahill ME, Bigio EH, Berry RW, Binder LI. Tau truncation during neurofibrillary tangle evolution in Alzheimer ’s disease. Neurobiol Aging 26(7):1015-22, 2005.
Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI. Early N terminal changes and caspase-6 cleavage of tau in Alzheimers disease. J Neurosci 24(36):7895-902, 2004.
Garcia-Sierra F, Ghoshal N, Quinn B, Berry RW, Binder LI. Conformational changes and truncation of tau protein during tangle evolution in Alzheimers disease. J Alzheimers Dis 5(2):65-77, 2003.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Tau (C3) Monoclonal Antibody, Purified (SIGNET)
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Tau (C3) Monoclonal Antibody, Purified (SIGNET)
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