- 询价
- R&D
- ZK-0100869
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
1 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- MART-1 (M2-7C10) Monoclonal Antibody, Purified (SIGNET)详细信息：
-
Description Purified Monoclonal Antibody against MART-1
(Formerly Signet Catalog Nos: 8160-01, 8160-26 L2 Predilute, 8160-36 LV Predilute)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone M2-7C10 Form Purified Antibody (in PBS + 0.1% NaN3 + 1% BSA) Host Mouse IsoType MART-1 (M2-7C10) Monoclonal Antibody, Purified (SIGNET)IgG2b Specificity This antibody recognizes MART-1 (Melan-A) [MART1, MART 1] an 18kDa transmembrane protein that is expressed in cells of melanocytic lineage. MART-1 is expressed by a large proportion of melanomas and by melanoma cell lines.
This antibody was generated against a MART-1 fusion protein.
Concentrated Format:
SIG-38160-1000 [1 mL]
Prediluted Formats:
SIG-38160-26 [6 mL] is ready-to-use with Biotin-based detection systems such as Signets USA Ultrastreptavidin Detection (SIG-32250).
SIG-38160-36 [6 mL] is ready-to-use with Biotin based detection systems on Ventana ES and Ventana NexES automated immunostainers.Uses This antibody is effective in immunohistochemistry (IHC). Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - IHC: ≥1:40 (concentrated format) for Biotin based detection systems such as Signets USA Ultrastreptavidin Detection (SIG-32250).
Tissue Sections: Formalin-fixed, paraffin-embedded tissues
Pretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as Retrieve-All 1 (SIG-31910).
Incubation: 20-60 minutes at room temperature
Notes MART-1 (M2-7C10) Monoclonal Antibody, Purified (SIGNET)Positive tissue (human): Melanoma Storage Store between 2-8°C. References Shidham VB, et al. Evaluation of micrometastases in sentinel lymph nodes of cutaneous melanoma: Higher diagnostic accuracy with Melan-A and MART 1 compared with S100 protein and HMB-45. Am. J. Surg. Pathol. 25(8):1039-1046, 2001.
Fetsch PA, et al. Melanoma-Associated Antigen Recognized by T Cells (MART-1). The advent of a preferred immunocytochemical antibody for the diagnosis of metastatic melanoma with fine-needle aspiration. Cancer Cytopath. 87:37-42, 1999.
Yu LL, et al. Detection of microscopic melanoma metastases in sentinel lymph nodes.Cancer 86 (4):617-627, 1999.
Beaty MW, et al. Effusion cytology of malignant melanoma. A morphological and immunological analysis including application of the Mart-1 antibody. Cancer (Cancer Cytopathology) 81:57-63, 1997.
Marincola FM, et al. Analysis of expression of the melanoma associated antigens Mart-1 and gp100 in metastatic melanoma cell lines and in situ lesions. J. Immunother. Emphasis Tumor Immunol 19:192-205, 1996.
Rivoltini L, et al. Induction of Tumor-Reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of the melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1. J. Immunol. 154:2257-2265, 1995.
Kawakami Y, et al. Identification of the immunodominant peptides of the Mart-1 human melanoma antigen recognized by the majority of HLA-A2 restricted tumor infiltrating lymphocytes. J. Exp. Med. 180:347-52, 1994.
Kawakami Y, et al. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad, Sci. USA 91:3515-3519, 1994.Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - IHC: ≥1:40 (concentrated format) for Biotin based detection systems such as Signets USA Ultrastreptavidin Detection (SIG-32250).
- MART-1 (M2-7C10) Monoclonal Antibody, Purified (SIGNET)
- zk-2904R LATS1肿瘤抑制基因LATS1抗体
zk-3247R Phospho-LIMK1(Thr508) + LIMK2(Thr505)磷酸化单丝氨酸蛋白激酶1/2抗体
zk-3246R Phospho-LATS1 (Ser909)磷酸化肿瘤抑制基因LATS1抗体
zk-3248R phospho-LKB1(Ser334)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
zk-3249R phospho-LKB1(Ser428)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
zk-3250R Phospho-LKB1(Thr189)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
zk-0456R GNRH黄体激素释放激素类似物抗体
zk-3254R Phospho-Lamin A + C(Ser22)磷酸化核纤层蛋白A/C抗体
zk-3255R Phospho-Lck (Tyr505)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体
zk-2906R Lyn膜相关蛋白酪氨酸激酶Lyn抗体
zk-3256R Phospho-Lyn (Tyr507)磷酸化膜相关蛋白酪氨酸激酶Lyn抗体
zk-3257R Phospho-Lyn (Tyr397)磷酸化膜相关蛋白酪氨酸激酶Lyn抗体
zk-1974R LRRC4脑瘤相关基因抗体
zk-11091R LSAMP大脑边缘系统相关膜蛋白抗体
zk-11087R LRFN2神经突触粘附样分子1抗体
zk-11089R LRFN4富含亮氨酸重复序列/Ⅲ型纤维连接蛋白4抗体
zk-11056R Laminin alpha 4层粘蛋白α4抗体(Lamininα4)
zk-11055R Laminin alpha 4层粘蛋白α4抗体(Lamininα4)
zk-11286R lipocalin 1脂质运载蛋白1抗体
zk-11287R Lymphotactin淋巴细胞趋化因子抗体
zk-11590R LRP5L低密度脂蛋白受体5样蛋白抗体
zk-11571R LRRTM3富含亮氨酸重复跨膜神经元蛋白3抗体
zk-6439R Lens culinaris agglutinin扁豆凝集素
zk-11786R phospho-LRRK2(Thr1410)磷酸化富亮氨酸重复激酶2抗体
zk-0961M Leptin receptor瘦素受体抗体
zk-11057R Elastin项韧带弹性蛋白抗体
zk-8574R ox-LDL氧化低密度脂蛋白抗体
zk-5779R LTBP4转化生长因子β结合蛋白4抗体
zk-5765R LANCL2G蛋白偶联受体69B
zk-4581R Listeria tropina李斯特菌菌体蛋白抗体
zk-4213R LARGRho的鸟嘌呤核苷酸交换因子12抗体
zk-6395R LEU5白血病相关蛋白5抗体
zk-7809R LRRC62富含亮氨酸重复蛋白62抗体
zk-6963R LPAP淋巴细胞磷蛋白磷酸酶相关蛋白抗体
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
MART-1 (M2-7C10) Monoclonal Antibody, Purified (SIGNET)
询价
