- $2536
- Alomone
- ZK-0039443
- 以色列
- 2025年11月20日
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- 详细信息
- 技术资料
- 供应商：
上海再康生物科技有限公司
- 库存：
大量
- 靶点：
见官方网站
- 级别：
高
- 目录编号：
AK-224
- 克隆性：
多克隆
- 抗原来源：
见 说 明 书
- 保质期：
6个月
- 抗体英文名：
TTX-Sensitive NaV Channel Antibody Explorer Kit
- 抗体名：
TTX-Sensitive NaV Channel Antibody Explorer Kit
- 标记物：
见官方网站
- 宿主：
见 说 明 书
- 适应物种：
见官方网站
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
液体或冻干粉
- 应用范围：
见官方网站
- 浓度：
见官方网站
- 保存条件：
-20°C
- 规格：
24 Vials
TTX-Sensitive NaV Channel Antibody Explorer Kit
A Screening Package of TTX-Sensitive NaV Channel Antibodies Economically PricedCat #: AK-224
24 Vials
Alomone Labs is pleased to offer the TTX-Sensitive NaV Channel Antibody Explorer Kit (#AK-224). This Explorer Kit includes antibodies targeted against voltage-gated Na+ channels along with their respective peptide control antigen. An ideal tool for screening purposes.
- Compounds
- Scientific Background
| Product Name | Cat # | Size |
|---|---|---|
Anti-NaV1.1 |
ASC-001 | 1 x 50 µl |
Guinea pig Anti-NaV1.1 |
AGP-043 | 1 x 50 µl |
Anti-NaV1.3 |
ASC-004 | 1 x 50 µl |
Anti-NaV1.3 (extracellular) |
ASC-023 | 1 x 50 µl |
Anti-NaV1.4 |
ASC-020 | 1 x 50 µl |
Anti-NaV1.6 |
ASC-009 | 1 x 50 µl |
Anti-NaV1.7 (extracellular) |
ASC-027 | 1 x 50 µl |
Anti-Pan NaV |
ASC-003 | 1 x 50 µl |
Guinea pig Anti-Pan NaV |
AGP-007 | 1 x 50 µl |
Anti-NaVβ1 (extracellular) |
ASC-041 | 1 x 50 µl |
Anti-NaVβ2 |
ASC-007 | 1 x 50 µl |
Anti-NaVβ4 (extracellular) |
ASC-044 | 1 x 50 µl |
Note Guinea pig polyclonal antibodies (#AGP-043, #AGP-026, AGP-057 & #AGP-007) are included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
Scientific Background
Voltage-gated sodium channels (Nav) are essential for the generation of action potentials and for cell excitability.1 Nav channels are activated in response to depolarization and selectively allow flow of Na+ ions.
To date, nine Nav α subunits have been cloned and named Nav1.1-Nav1.9.4-5 The Nav channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive (Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7) and TTX-resistant (Nav1.5, Nav1.8 and Nav1.9).2-3 Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific.
TTX-Sensitive NaV Channel Antibody Explorer KitReferences
- Lai, J. et al. (2003) Curr. Opin. Neurobiol. 13, 291.
- Fang, X. et al. (2002) J. Neurosci. 22, 7425.
- Wu, L. et al. (2002) Neuro. Report. 13, 2547.
- Baker, M.D. and Wood, J.N. (2001) Trends. Pharmacol. Sci. 22, 27.
- Fjell, J. et al. (2000) Neuro. Report. 11, 199.
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