- $1585
- Alomone
- ZK-0039440
- 以色列
- 2025年11月20日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海再康生物科技有限公司
- 库存：
大量
- 靶点：
见官方网站
- 级别：
高
- 目录编号：
AK-430
- 克隆性：
多克隆
- 抗原来源：
见 说 明 书
- 保质期：
6个月
- 抗体英文名：
Neuronal Adhesion Molecule Antibody Explorer Kit
- 抗体名：
Neuronal Adhesion Molecule Antibody Explorer Kit
- 标记物：
见官方网站
- 宿主：
见 说 明 书
- 适应物种：
见官方网站
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
液体或冻干粉
- 应用范围：
见官方网站
- 浓度：
见官方网站
- 保存条件：
-20°C
- 规格：
20 Vials
Neuronal Adhesion Molecule Antibody Explorer Kit
A Screening Package of Neuronal Adhesion Molecule Antibodies for Economically PricedCat #: AK-430
20 Vials
Alomone Labs is pleased to offer the Neuronal Adhesion Molecule Antibody Explorer Kit (#AK-430). This Explorer Kit includes neuronal adhesion molecule antibodies, ideal for screening purposes.
- Compounds
- Scientific Background
| Product Name | Cat # | Size |
|---|---|---|
Anti-Neurexin 1α (extracellular) |
ANR-031 | 1 x 50 µl |
Anti-Neurexin 3α (extracellular) |
ANR-033 | 1 x 50 µl |
Anti-Neuroligin 1 (extracellular) |
ANR-035 | 1 x 50 µl |
Anti-Neuroligin 2 (extracellular) |
ANR-036 | 1 x 50 µl |
Anti-Neural Cell Adhesion Molecule 1 (extracellular) |
ANR-041 | 1 x 50 µl |
Anti-Nectin-1 (extracellular) |
ANR-051 | 1 x 50 µl |
Anti-Nectin-2 (extracellular) |
ANR-052 | 1 x 50 µl |
Anti-N-Cadherin |
ANR-082 | 1 x 50 µl |
Anti-Neuroplastin (extracellular) |
ANR-090 | 1 x 50 µl |
Anti-Caspr2 |
APZ-005 | 1 x 50 µl |
Neuronal Adhesion Molecule Antibody Explorer KitScientific Background
Neuroligins (NLGNs) are family of postsynaptic cell adhesion molecules that play an important role in synaptic development and function1. Four genes encode for the different members of the neuroligin family in mammals: NLGN 1-4, which are differentially enriched in postsynaptic specializations of synapses2. Neuroligin 2 (NLGN2) is expressed in neurons in the brain and also in pancreatic β cells where it facilitates insulin secretion3.
Neurexins (NRXNs) are a family of transmembrane, synaptic adhesion molecules. NRXNS were identified as receptors for α-latrotoxin, a presynaptic toxin that triggers massive neurotransmitter release4. Neurexins are largely presynaptic proteins that form a trans-synaptic cell-adhesion complex with postsynaptic neuroligins5. They are encoded by three genes (NRXN1, NRXN2 and NRXN3).
Nectins, which were originally identified as virus receptors, are members of the cell-cell adhesion molecule (CAM) family. They are Ca2+-independent immunoglobulin-like CAMs. The nectin family comprises four members, nectin-1, nectin-2, nectin-3 and nectin-4, which are encoded by the PVRL1, PVRL2, PVRL3 and PVRL4 genes, respectively6. In the central nervous system, these cell adhesion molecules aggregate in formations, termed puncta adherentia junctions, which are mechanical adhesive sites that connect pre- and postsynaptic membranes7.
References
- Chubykin, A.A. et al. (2007) Neuron 54, 919.
- Kohl, C. et al. (2013) PLoS ONE 8, e5687.
- Suckow, A.T. et al. (2024) Endocrinology 149, 6006.
- Ichtchenko, K. et al. (1995) Cell 81, 435.
- Mosedale, M. et al. (2012) J. Biol. Chem. 287, 6350.
- Rikitake, Y. et al. (2012) J. Cell Sci. 125, 3713.
- Fantin, M. et al. (2013) PLoS One 8, e56897.
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文献和实验Construction and Purification of Adhesion Molecule Immunoglobulin Chimeric Proteins
for a given cell-surface molecule. Particularly useful in this respect have been soluble forms of proteins created by fusing the extracellular domains of the protein of interest to the Fc part of an antibody molecule (1 ). The resulting dimeric proteins
Neuronal Growth-Promoting and Inhibitory Cues in Neuroprotection and Neuroregeneration
cone, of guidance cues that determine the pathway taken by the axons. These guidance cues can act to promote and/or repel growth cone advance. The directed growth of axons is partly governed by cell adhesion molecules (CAMs) on the neuronal growth cone
【资源】[共享]Adhesion Protein Protocols——（很有用的）
for the Discovery of New Adhesion Molecule Family Member... 1— Introduction 2— Materials 3— Method 4— Notes Acknowledgments References 7— Construction and Purification of Adhesion Molecule Immunoglobulin Chimeric Proteins 1— Introduction 2—
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