- $550
- Alomone
- ZK-0039323
- 以色列
- 2025年11月20日
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- 详细信息
- 技术资料
- 供应商：
上海再康生物科技有限公司
- 库存：
大量
- 靶点：
见官方网站
- 级别：
高
- 目录编号：
ESB-01200
- 克隆性：
多克隆
- 抗原来源：
见 说 明 书
- 保质期：
6个月
- 抗体英文名：
ASIC1 Channel Basic Research Pack
- 抗体名：
ASIC1 Channel Basic Research Pack
- 标记物：
见官方网站
- 宿主：
见 说 明 书
- 适应物种：
见官方网站
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
液体或冻干粉
- 应用范围：
见官方网站
- 浓度：
见官方网站
- 保存条件：
-20°C
- 规格：
6 Vials
ASIC1 Channel Basic Research Pack
All You Need for ASIC1 Channel ResearchCat #: ESB-01200
6 Vials
Alomone Labs is pleased to offer the ASIC1 Channel Basic Research Pack (#ESB-200). The Research Pack contains all you need for ASIC1 channel research: Antibodies recognizing different domains of the channel and a specific ASIC1 blocker and activator, all in one economical package!
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-ASIC1 |
ASC-014 | 1 x 0.2 ml |
Anti-pan ASIC (extracellular) |
ASC-031 | 1 x 0.2 ml |
MitTx |
M-100 | 1 x 20 µg |
Psalmotoxin-1 |
STP-200 | 1 x 0.1 mg |
Scientific Background
ASIC1 is a member of a family of Na+ channels that are activated by external protons. The family includes another three members ASIC2, ASIC3 and ASIC4.
The ASICs are in fact part of a larger superfamily termed epithelial Na+ channels (EnaC) and share with it the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N- and C- termini.
There are two recognized splice variants of the ASIC1 gene that differ on their N-termini, ASIC1a and ASIC1b that have different tissue distributions and functions.
The ASIC1 responds to a decrease in extracellular pH with an inward cation current that is quickly inactivated despite the continuous presence of protons in the medium.
Lately, ASIC1 has been implicated in processes such as learning and memory in the central nervous system.
ASIC1 Channel Basic Research PackReferences
- Kellenberger, S. et al. (2002) Physiol. Rev. 82, 735.
- Wemmie, J. A. et al. (2002) Neuron 34, 463.
- Wemmie, J. A. et al. (2003) J. Neurosci. 23, 5496.
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