Anti-NGAL (human)

Anti-NGAL (human)

Cat. No.

ABS 062-14B

Product name

Anti-NGAL (human)

Description

Mouse monoclonal antibody, biotinylated

Specificity

ABS 062-14 is specific for human NGAL (neutrophil gelatinase-associated lipocalin)

Immunogen

Human recombinant NGAL coupled to carrier 

Application

ELISA

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG2a/k

Gene ID

3934

Clone number

14

Epitope

Differs from those of HYB 211-01, the ABS 038 series of antibodies and ABS 062-33.

Content

50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Biotinylated

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.