- 询价
- R&D
- ZK-0002899
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Peripherin 7C5 Monoclonal Antibody保存于运输说明：
- Store at -20°C
- 详细信息：
-
Description Monoclonal Antibody against Peripherin Clone 7C5 Form Purified Antibody (contains 10mM sodium azide in PBS) Host Mouse Species Reactivity Mammalian, maybe Chicken IsoType Peripherin 7C5 Monoclonal AntibodyIgG1, k light chain [Ab] 0.5 mg/mL Specificity Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems. Subsequently peripherin was found in sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrigs disease and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes.
Antibody 7C5 was raised against recombinant rat peripherin purified from E. coli. The clone was initially screened on ELISA of the immunogen, and subsequently tested on sections of rat brain. 7C5 was one of several clones which stained processes expected to be peripherin positive. Studies indicated that 7C5 is relatively insensitive to aldehyde fixation and is therefore superior to clone 8G2, a widely used anti-peripherin monoclonal antibody.Uses Peripherin 7C5 Monoclonal AntibodyThis antibody is effective in immunoblotting and immunocytochemistry. Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval. - Western blot: 1:5,000*
- Immunofluorescence: 1:1,000
Notes * Predicted MW = 57kD Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long term storage keep this antibody at -80°. References Errante LD, Wiche G, Shaw G. Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system J. Neurosci. Res. 37:515-528, 1994. Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - Peripherin 7C5 Monoclonal Antibody
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Peripherin 7C5 Monoclonal Antibody
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