Melanoma (HMB45) Monoclonal Antibody

Melanoma (HMB45) Monoclonal An

tibody
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  • 询价
  • R&D
  • ZK-0002635
  • 美国/中国
  • 2025年11月20日
  • 科研使用
  • Goat,Rabbit,Mouse
  • 人,大鼠,小鼠,兔
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  • 企业认证

    • 详细信息
    • 技术资料
    • 靶点

      来电咨询

    • 克隆性

      多克隆

    • 标记物

      见 说 明 书

    • 宿主

      Goat,Rabbit,Mouse

    • 适应物种

      人,大鼠,小鼠,兔

    • 形态

      液态/粉状

    • 应用范围

      科研使用

    • 浓度

      1mg/1ml

    • 保存条件

      -20℃保存

    • Melanoma (HMB45) Monoclonal Antibody详细信息:
    • Description Monoclonal Antibody against Anti-Melanoma, HMB45
      Clone HMB45
      Form Affinity Purified Antibody (in PBS, 1% BSA and 0.1% sodium azide)
      Host Mouse
      Species Reactivity Human
      IsoType IgG1
      Specificity Melanoma (HMB45) Monoclonal Antibody HMB45 reacts with a melanoma-specific antigen present in melanocytic cells and junctional nevi. The antibody does not react with normal melanocytes nor intradermal nevus cells. It is also nonreactive with other neoplasms including sarcomas, carcinomas and glial tumors.
      Uses This antibody can be used for staining of paraffin-embedded tissue sections fixed in neutral buffered formalin and is compatible with most commonly used histological fixatives. Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection.
      Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. This antibody is sold for laboratory research use only, not for human or in-vivo use. Covance antibodies may not be resold or modified for resale without prior written approval.
      • Immunohistopathology: 1:50
      Notes This antibody is distributed by arrangement with Enzo Biochem Corporation.
      Storage Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. Long term storage should be at -80°C. This shelf-life of this product is approximately 1 year.
      References Melanoma (HMB45) Monoclonal Antibody Ordonez NG, Xiaolong J, Hickey RC. Comparison of HMB-45 monoclonal antibody and S-100 protein in the immunohistochemical diagnosis of melanoma. Am. J. Clin. Path. 90:385-390, 1988.

      Wick MR, Stanley SJ, Swanson PE. Immunohistochemical diagnosis of sinonasal melanoma, carcinoma, and neuroblastoma with monoclonal antibodies HMB-45 and anti-synaptophysin. Arch. Path. Lab. Med. 112:616-620, 1988.

      Wick, M. R., Swanson, P. E. and Rocamora, A. Recognition of malignant melanoma by monoclonal antibody HMB-45. An immunohistochemical study of 200 paraffin-embedded cutaneous tumors. J. Cutan. Path. 15:201-207, 1988.

      Duray PH, Palazzo J, Gown AM, Ohuchi N. Melanoma cell heterogeneity: a study of two monoclonal antibodies compared with S-100 protein in paraffin sections. Cancer 61:2460-2468, 1988.

      Gown AM, et al. Monoclonal antibodies to a melanoma-specific cytoplasmic antigen.Lab. Invest. 52:25A, 1985.

      Gown AM, Vogel AM, Hoak D, Goush F, McNutt MA. Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am. J. Path. 123:195-203, 1986.
      Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval.
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