DNA拓普西异构酶ⅡA抗体

DNA拓普西异构酶ⅡA抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

DNA拓普西异构酶ⅡA抗体产品介绍

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
mol wt:174kDa
Other Aliases:
Topoisomerase Ⅱalpha; DNA topoisomerase II, alpha isozyme; DNA topoisomerase 2 alpha; DNA topoisomerase II 170 kD; DNA Topoisomerase2; TOP2; TOP2A; TopII alpha; Topo II alpha; Topoisomerase DNA II alpha 170kDa; Topoisomerase II alpha 170 kDa; TP2A; TPⅡA

zk-1840R Lamin B核纤层蛋白B抗体(细胞核膜标志物)
zk-1841R lamin A + C核纤层蛋白A/C抗体
zk-1845R LRIG2LRIG2抗体
zk-1843R LEF-1淋巴增强因子-1抗体
zk-1844R LRIG1LRIG1抗体
zk-1846R LRIG3LRIG3抗体
zk-1617R LI-cadherin肝肠钙粘连蛋白抗体
zk-1842R Layilin透明质酸受体抗体
zk-9649R C17orf8217号染色体开放阅读框82抗体
zk-11874R LMCD1转录因子LMCD1抗体
zk-12336R Ly76淋巴细胞抗原76抗体
zk-9509R LRP15富含亮氨酸重复序列LRP15抗体
zk-11213R LRRTM1富含亮氨酸重复跨膜神经元蛋白1抗体
zk-8561R Laminin 2 alpha层粘蛋白α2抗体
zk-6762R LIPG内皮脂肪酶抗体
zk-4206R sLOX 1可溶性凝集素样氧化低密度脂蛋白受体1抗体
zk-7504R Laminin Beta 2层粘连蛋白β2抗体
zk-7516R LECT1白细胞衍生化学吸引素抗体
zk-8430R LMO2T淋巴细胞易位蛋白2抗体
zk-11463R Liprin alpha 1酪氨酸磷酸酶受体相互作用蛋白Liprin α1抗体
zk-4245R LONP1线粒体离子肽酶1抗体
zk-6230R LC3C微管相关蛋白轻链3C抗体
zk-5705R LZTS1假定肿瘤抑制亮氨酸拉链蛋白1抗体
zk-3827R LDHC(Cancer,testis antigen 32)乳酸脱氢酶LDH-C（肿瘤/睾丸抗原32）抗体
zk-6090R LUCA15肿瘤抑制基因LUCA15抗体
zk-9193R LST1淋巴细胞特异性转运蛋白1抗体
zk-4118R LEO1RNA聚合酶相关蛋白LEO1抗体
zk-5408R Phospho-LRP6(Thr1479)磷酸化低密度脂蛋白受体相关蛋白6抗体