细胞角蛋白8抗体

细胞角蛋白8抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

细胞角蛋白8抗体产品介绍

结构蛋白（Structural Proteins）
上皮细胞胞质中的骨架蛋白除微丝（肌动蛋白）、微管蛋白外，主要是细胞角蛋白（cytokeratins，CK）。CK8也是上皮细胞的特征性标记物。
Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18. Cytokeratin 8 is primarily found in the non squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18.
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 – 7.8.
The individual cytokeratin polypeptides are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.
Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
mol wt:42kDa
Other Aliases:
Cytokeratin 8; CK8 (card2; Cardiac autoantigen 2 120kD; CK 8; ck8; Cyk 8; cyk8; Cytokeratin 8; Cytokeratin8; k0; k2c8; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin8; KO; Krt 8; krt8; CYKER; Krt2-8zk-6518R CDK5RAP3周期素依赖性激酶5激活结合蛋白C53抗体
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zk-6042R Cystatin E半胱氨酸蛋白酶抑制剂6抗体
zk-6024R CA10碳 酸 酐酶相关蛋白/脑蛋白10抗体
zk-2615R IL-18R alpha/CD218a白细胞介素-18受体α链抗体
zk-3778R CTCF转录阻抑蛋白CTCF抗体
zk-3786R CD1aT淋巴细胞CD1抗体
zk-4000R Phospho-CHK2 (ser19)磷酸化细胞周期检测点激酶2抗体
zk-2932R Clathrin heavy chain网格蛋白重链抗体
zk-3845R CD168透明质酸介导细胞游走受体抗体
zk-9804R C2orf242号染色体开放阅读框24抗体
zk-9809R C2orf602号染色体开放阅读框60抗体
zk-5248R phospho-CDK7 (Thr170)磷酸化周期素依赖性激酶7抗体
zk-5249R Phospho-CDK9 (Thr29)磷酸化周期素依赖性激酶9抗体
zk-5250R phospho-CHEK1 (Ser280)磷酸化细胞周期检测点激酶1抗体
zk-5251R phospho-CHEK1(Ser317)磷酸化细胞周期检测点激酶1抗体
zk-5253R phospho-CDKN2A (Ser140)磷酸化抑癌基因p16抗体
zk-5254R phospho-CDKN2A (Ser152)磷酸化抑癌基因p16抗体
zk-5255R phospho-CDKN2A (Ser8)磷酸化抑癌基因p16抗体
zk-5256R phospho-CREB-1(Ser129)磷酸化CREB-1抗体
zk-5252R phospho-CSF2RB (Tyr766)磷酸化粒细胞-巨噬细胞集落刺激因子受体β抗体
zk-5263R phospho-CDH2 (Tyr820)磷酸化N-钙粘附分子抗体
zk-5268R phospho-CDC27 (Thr244)磷酸化后期促进复合蛋白3抗体
zk-5184R phospho-c-Abl(Tyr283)磷酸化非受体酪氨酸激酶c-Abl抗体
zk-5183R phospho-c-Abl(Thr735)磷酸化非受体酪氨酸激酶c-Abl抗体
zk-15341R C9orf759号染色体开放阅读框75抗体
zk-0647R CD4CD4抗体
细胞角蛋白8抗体